Alkaloids from the South China Sea Black Coral Antipathes dichotoma.

نویسندگان

  • Shu-Hua Qi
  • Guo-Chen Su
  • Yi-Fei Wang
  • Qiu-Ying Liu
  • Cheng-Hai Gao
چکیده

A new carbazole alkaloid, antipathine A (1), together with three known zoanthoxanthin alkaloids (2--4) was isolated from the EtOH/CH2Cl2 extracts of the South China Sea black coral Antipathes dichotoma. The structure of 1 was determined on the bases of extensive spectroscopic analysis, including 1D and 2D NMR data. Compounds 1 and 2 showed moderate cytotoxicity against human stomach carcinoma SGC-7901 cell line with IC50 of 67.38 and 86.40 microg/ml, respectively, and 1 and 2 also showed weak cytotoxicity toward human liver carcinoma Hep_G2 cell line.

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عنوان ژورنال:
  • Chemical & pharmaceutical bulletin

دوره 57 1  شماره 

صفحات  -

تاریخ انتشار 2009